Does Mounjaro Cause Hair Loss?
- SkinnyJab
- Sep 28
- 3 min read
Updated: Oct 4
👉 Hair loss is not a known direct side effect of Mounjaro (tirzepatide).In clinical trials, hair loss was not reported as a common adverse event.
However, some patients do notice hair thinning while on Mounjaro or other GLP-1 medications (like Wegovy or Ozempic). This usually isn’t from the drug itself, but from:
🔎 Possible reasons
Rapid weight loss → Sudden calorie reduction or big weight changes can trigger telogen effluvium, a temporary shedding phase where hair follicles reset.
Nutritional deficiencies → Low protein, iron, zinc, or vitamins during weight loss can impact hair growth.
Hormonal shifts → Weight changes affect hormones and metabolism, which can indirectly affect hair.
Stress on the body → Any major change (illness, surgery, big weight drop) can temporarily cause hair shedding.
🌿 The good news
Supporting with adequate protein, vitamins, and minerals helps reduce the risk.
Slower, steady weight loss (rather than very rapid) is gentler on the body and hair.
✅ Summary for patients: New research is indicating that Mounjaro and other GLP- Medications may directly be the cause hair loss. They seem to promote the activation of DHT (dihydrotestosterone)which is a hormaine related to hair loss. Natural DHT inhibitors include Pumpkin seed oil capsules and rosemary oil

Here’s a balanced, evidence-informed look at natural supplements (and botanicals) that may help with hair loss, along with important caveats. Always advise patients to check with their clinician or pharmacist before starting anything new (interactions, safety, and cause of hair loss vary).
🔍 What the Evidence Says — Vitamins, Minerals & Botanicals
1. Iron / Ferritin
Among the stronger links: iron deficiency (or low ferritin) is associated with hair shedding (especially telogen effluvium) in women. PMC+1
If labs show deficiency, supplementing appropriately may help. But in those with normal iron stores, excess iron can be harmful.
2. Vitamin D
Some studies suggest people with hair loss have lower vitamin D levels. PMC
Repleting a deficiency may support hair health, though evidence that extra supplementation beyond normal isn’t conclusive.
3. Zinc
Zinc deficiency is occasionally implicated in hair shedding, though data are inconsistent. PMC
Too much zinc can suppress copper and cause imbalance, so dosing must be cautious.
4. Biotin (Vitamin B7)
Biotin deficiency can cause hair loss, but true deficiency is rare. PMC+1
Supplementing biotin in people without deficiency hasn’t been reliably shown to help hair growth.
5. Botanical / Herbal Options
Rosemary oil (topical) — Some trials show that rosemary oil applied to the scalp performs similarly to 2% minoxidil over months for androgenetic alopecia. PMC
Saw palmetto — Thought to have mild anti-androgen (5α-reductase inhibition) properties. Evidence is limited, results modest.
Other herbs (pumpkin seed, etc.) have seen small preliminary studies, but none with strong clinical backing. However this research is gathering good positive outcomes for those using these products
⚠️ Cautions & Realistic Expectations
Natural does not mean risk-free — interactions or side effects are possible.
Supplements only help if a deficiency or reversible contributing factor exists. They are rarely enough by themselves for advanced hair loss (genetic/hormonal causes).
Over-supplementation (e.g. too much vitamin A, selenium) can cause hair loss.
Diagnosis first: you need to identify the cause (nutritional, hormonal, autoimmune, scalp disease, medication side effect).
If you have any concerns regarding hair loss or thinning, it is advisible to seek professional medical advice
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